Advance, hold, monitor or stop.
Every brief opens with the call, and the conditions attached to it — not a wall of findings to interpret yourself.
Decision Support tool · Gate Brief · Prototype v0
Start with a CAS. Leave with a decision.
brick42 Gate Brief turns a molecule into a cited Stage-Gate brief — what is known, what remains unresolved, and whether expert diligence should begin now. Free, confidential and anonymous.
What a brief gives you
A decision instrument, not a data dump.
Source, date, confidence, conflict, caveat.
Each claim carries its provenance, so the uncertainty is visible rather than smoothed over.
Reverse-plan an EU launch.
Working back from a target market entry using editable assumptions, so timing becomes a decision input.
How it works
Three rules the brief never breaks.
Identity before intelligence
A valid checksum is not enough. Parent, salt, solvate and product context are confirmed before any risk is read into the molecule.
Directional, never definitive
Containment, supply filings and launch timing expose evidence and uncertainty — not a claim of manufacturing certainty.
A practical next gate
Route and IP screening, CMO capability and staged NRE work become a scoped brick42 diligence request.
Try it
A reviewed example, answered on the spot.
Enter a CAS number or an API name. Reviewed molecules return a Gate Brief immediately; a commodity chemical such as acetone is routed toward suppliers instead.
Reviewed example · anonymisedreturns a brief
| Input | CAS number or API name |
| Reviewed example | a recent oncology API |
| Returns | advance · hold · monitor · stop |
An unidentified name is sent to NIH PubChem only to identify the chemical. The search is anonymous — no cookies, no tracking, no record of who is searching.
Confidentiality
Anonymous by design.
brick42 sets no cookies and keeps no record of who is searching. A molecule outside the reviewed set is sent to NIH PubChem only to identify the chemical, and that lookup is not tied to you. brick42 learns who you are only if you write in.
Free · confidential
Bring a molecule. Leave with a recommendation.
If a brief says the next gate is a scoped review, that is exactly where brick42's R&D work begins.